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Product Name | Sulfadimidine | ![]() |
CAS No. | 57-68-1 | |
MF | C12H14N4O2S | |
MW | 278.33 |
Features:
Sulfadimidine is a broad-spectrum bacteriostatic agent. Its p-aminobenzoic acid (PABA) can compete with PABA to act on difolate synthetase in bacteria, thereby preventing PABA from being used as raw material to synthesize folate required by bacteria and reducing the amount of metabolically active tetrahydrofolate. The latter is essential for bacterial synthesis of purine, thymine nucleoside Chemicalbook and deoxyribonucleic acid (DNA). Therefore, sulfadiazine can inhibit the growth and reproduction of bacteria. The effect of sulfadiazine is antagonized by PABA and its derivatives (procaine, tetracaine), as well as by the presence of pus and tissue breakdown products, which provide essential substances for bacterial growth.
Compound:
The mixture of p-acetaminobenzene sulfonyl chloride (1.0mmol) and cycloamine (1.5mmol) in water (1mL) was stirred for 5 minutes and the resulting precipitate was collected through filtration. Transfer it to a round-bottomed flask and add 2mL of the concentrated solution. 4ml of water. Boil the reaction mixture gently at 100°C for one hour. The solution obtained in an ice bath is cooled and alkalized using a saturated NaHCO3 aqueous solution. The granular sediment is filtered, washed with water, and dried in the air to obtain the product sulfadimidine.
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A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
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A6 Different quantity has different discount.
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