Customization: | Available |
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Varieties: | General Disease Prevention Medicine |
Component: | Animal |
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Product name |
G S-441524
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CAS No. | 1 191237-69-0 |
MF | C12H13N5O4 |
MW | 291.26 |
EINECS | 200-001-8 |
Features:
01.G S-441524 is a small molecule, scientifically known as a nucleoside triphosphate competitive inhibitor, which exhibits strong antiviral activity against many RNA viruses.
02.It can inhibit the replication of several different types of RNA viruses, such as the zoonotic severe acute Respiratory syndrome (SARS) coronavirus, Middle East Respiratory Syndrome virus, Ebola virus, Lassa fever virus, Junin virus and respiratory syncytial virus, etc. At the same time, it has low cytotoxicity in a wide range of cell lines.
03.G S-441524 is the second targeted antiviral drug for the treatment of feline infectious peritonitis (FIP) after GC376. G S-441524 is a small molecule nucleotide analogue provided by GileadSciences(the NO.1 in the global antiviral field) to the Perdersen Lab 2 and its infectious peritonitis research topic at the University of California, Davis (the NO.1 in the global Chemicalbook veterinary field).
04.It is a reverse transcriptase inhibitor that can inhibit the replication of feline infectious peritonitis virus (FIP) and is a prerequisite molecule for the synthesis of nucleoside triphosphate with pharmacological activity.
USE:
01.G S-441524 is phosphorylated into nucleoside monophosphate (NMP) through cellular kinases within cells, and then transformed into an active triphosphate metabolite (NTP structural analogue). In viral RNA synthesis, active NTP structural analogues act as competitors of natural triphosphate nucleosides, competing with natural nucleosides (ATP, TTP, CTP, GTP) for RNA transcription. When the G S-441524 molecule is inserted into the transcription product, the transcription will be prematurely terminated, thereby inhibiting the viral RNA transcription process.es.
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Q1 Can i get some samples
A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2 How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T
Q3 How to confirm the Product Quality before placing orders
A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4 What's your MOQ
A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5 How about delivery leadtime
A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6 Is there a discount
A6 Different quantity has different discount.
Q7 How do you treat quality complaint
A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q8 How to contact us
A8 You can chat with us by Trademanager,MSN&Skype Online.
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