Top quality High Purity 99% Peptide Cyclosporin a Powder
| Product |
Cyclosporin a |
|
| CAS |
59865-13-3 |
| MF |
C62H111N11O12 |
| MW |
1202.61 |
| melting point |
148-151ºC |
| density |
0.9913 |
Cyclosporin A is a strong immunosuppressant, inhibits the onset of the reaction in cell media, reversibly inhibits T cell proliferation, does not inhibit the generation of blood cells, does not affect the function of the phagocyte. As compared with other inhibitors, fewer advantages are induce or aggravate infection, mainly used in clinical kidney, liver, heart, lung, bone marrow transplant anti-rejection, can be combined with adrenal corticosteroids, but not in combination with other immunosuppressive agents. Also used in certain autoimmune diseases (such as systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, autoimmune hemolytic anemia). Try to uveitis, severe aplastic anemia, refractory idiopathic thrombocytopenic purpura, psoriasis, etc.
Cyclosporin A is a lipophilic cyclic peptide compounds separated by certain Hyphomycetes fungi, such as Cylindrocarpon lucidum and Tolypocladium inflatumculture medium. In 1980s, as an immunosuppressant, it has been widely used in the world, is now used for a variety of tissues and organ transplant to prevent rejection reaction and to treat autoimmune diseases.It is often used in the prevention of rejection of various tissues and organs transplantation and the treatment of some immune diseases. It is also used in kidney disease, aplastic anemia and refractory ulcerative colitis. It has been used in dermatology for refractory skin diseases, and the best curative effect is for severe psoriasis (including vulgaris, pustular, erythroderma, and arthropathy). Cutaneous Chemicalbook diseases with good curative effect include Behcet's disease, pyoderma gangrenosum, lichen planus, epidermolysis bullosa acquired, etc. "Conditions with moderate efficacy are alopecia general, atopic dermatitis, chronic actinic dermatitis, actinic reticulocytosis, adult linear IgA bullous dermatitis, pemphigus, and bullous pemphigoid (the latter two conditions are associated with concomitant glucocorticoids)."
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