| Customization: | Available |
|---|---|
| Varieties: | Parasite Disease Prevention Medicine |
| Component: | Animal |
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| Product Name | Selamectin | |
| CAS No. | 220119-17-5 | |
| MF | C43H63NO11 | |
| MW | 769.97 | |
| EINECS | 815-979-7 |
Features:
01.Seramectin (also known as seramectin) is produced by the fermentation of a new strain of Streptomyces aviviae genetically reprogrammed, developed by P in the United States, by chemically synthesizing structural modifications to Dolamectin.
02.The mechanism of action of seramectin is the same as that of other abamectin drugs. On the one hand, seramectin can act as an agonist of GABA to trigger the release of presynaptic GABA, thus causing the increase of membrane permeability to Cl¯; on the other hand, the drug can open the chloride ion channels controlled by glutamate, resulting in the increase of Cl¯ permeability leading to membrane potential hyperpolarization.
03.Thus blocking the transmission of nerve signals, causing rapid, fatal and non-chemicalbook spastic neuromuscular paralysis and death. Since flukes and tapeworms do not have GABA neurotransmitter and glutamate-controlled Cl¯ channels, these drugs have no repellent effect on them.
04.The drug binding site of invertebrates is in peripheral tissues, while the drug binding site of mammals is in the central nervous system. Due to the effect of the blood-brain barrier, such drugs rarely enter the brain tissue, so such drugs are safe for most mammals.
USE:
01.The safety of seramectin has been greatly improved, and both oral and injection have good effects. Seramectin is a kind of in vivo and in vitro insecticide mainly for adult fleas, filaria and mange in pet cats and dogs.
02.Selamectin, a semi-synthetic macrolide, is an antiparasitic agent and insect repellent. Selamectin activation of neurons and the pharyngeal muscle glutamic acid chlorine ion channel gating (glutamate - gatedchlorChemicalbookidechannels), in order to prevent the evil silk worm, lymphatic silk worm and worm infections. Selamectin is also a potent P-glycoprotein substrate and inhibitor with an IC50 of 120nM.
1.We have a professional and efficient team that can meet your various needs.
2.Have rich knowledge and sales experience in chemical products, and have in-depth research on the use of products and how to maximize their effects.
3.The system is sound, from supply to production, packaging, quality inspection, after-sales, and from quality to service to ensure customer satisfaction.
4.Price advantage. On the premise of ensuring quality, we will give you the best price to help maximize customers' interests.
5.Transportation advantages, air, sea, land, express, all have dedicated agents to take care of it. No matter what transportation method you want to take, we can do it.
Q1 Can i get some samples
A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2 How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T
Q3 How to confirm the Product Quality before placing orders
A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4 What's your MOQ
A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5 How about delivery leadtime
A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6 Is there a discount
A6 Different quantity has different discount.
Q7 How do you treat quality complaint
A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q8 How to contact us
A8 You can chat with us by Trademanager,MSN&Skype Online.
You can choose your interested products and send inquiry to us.
You can dial our telephone directly or send Email to us, you will get our reply.
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