Veterinary API with Competitive Price GMP Quality Thiamphenicol CAS 15318-45-3

• Function: Drug Detoxification, Antidote
• Certification: GMP, FDA
• Grade Standard: Medicine Grade
• Type: Analysis reagent
• State: White Crystalline Powder
• Volatile: Not Volatile
• Model NO.: BP USP EP IN-HOUSE
• CAS: 125-04-2
• Mf: C12h15cl2no5s
• MW: 356.22
• Melting Point: 163-166 Degree Centigrade
• Shelf Life: 2years
• Transport Package: 25kg/Drum
• Specification: USP; EP; In-house
• Trademark: Jinan Andechem
• Origin: China
• HS Code: 2941400000
• Production Capacity: 10ton/Month

Product Description

Product Name: Thiamphenicol   
CAS NO.: 15318-45-3
Packing:25kg/drum
MF: C12H15Cl2NO5S

MW:356.22
Certificate:
Desceription:
Thiamphenicol is a broad-spectrum antibiotic chloramphenicol, which is more effective to the gram-negative bacteria than the gram-positive bacteria. At room temperature, it is a white to off-white crystalline powder or crystal, which can be quickly and completely absorped by oral adminstration, as well as it is excreted mainly in the prototype from the urine for metabolism. It is clinically applied for the treatment of respiratory, urinary tract, liver and gallbladder, typhoid and other intestinal surgery, gynecology and ENT infections. Especially in the mild infections it is more effective. It has the similar chemical structure with the chloramphenicol. Its methyl sulfone substituted the nitro of chloramphenicol, which reduced its toxicity, and in vivo its antibacterial activity is 2.5-5 times stronger than chloramphenicol. For gram-positive bacteria, such as streptococcus pneumoniae and hemolytic streptococcus, it has very strong antibacterial effect, while for gram-negative bacteria, such as Neisseria gonorrhoeae, meningococcus, lung Bacteroides, E. coli, Vibrio cholerae, Shigella and influenza bacillus, it also has strong antibacterial effect. For anaerobic bacteria, Rickettsia and amoeba, it has antibacterial effect in some extent. It has the same antimicrobial mechanism with chloramphenicol, which mainly inhibits the synthesis of bacterial protein. This drug is absorped quickly by oral administration, which reaches peak blood concentration within two hours. Its half-life is 5 hours, that is more longer than chloramphenicol. The bacteria have complete cross resistance to it and chloramphenicol, while the bacteria have some cross-resistance phenomenon to it and tetracycline.

Uses:
1. Thiamphenicol is a semi-synthetic chloramphenicol prepared by total synthesis from thiophenol in which the nitro moiety of chloramphenicol is replaced by a methylsulphone, first synthesised at Sterling Winthrop in 1952. Thiamphenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Thiamphenicol acts by binding to the 23S sub-unit of the 50S ribosome inhibiting protein synthesis.
2. Thiamphenicol has been extensively studied with over 800 literature citations.
3.Thiamphenicol is a semi-synthetic chloramphenicol prepared by total synthesis from thiophenol in which the nitro moiety of chloramphenicol is replaced by a methylsulphone, first synthesised at Sterling Winthrop in 1952.
4.Thiamphenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Thiamphenicol acts by binding to the 23S sub-unit of the 50S ribosome inhibiting protein synthesis.
5.Thiamphenicol has been extensively studied with over 800 literature citations.
6. It is generally less active than chloramphenicol, but is equally active against Str. pyogenes, Str. pneumoniae, H. influenzae and N. meningitidis, including some strains resistant to chloramphenicol. It is more actively bactericidal against Haemophilus and Neisseria spp.


Packing and Delivery:


FAQ:
Q1  Can i get some samples
A1  Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2  How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T
Q3  How to confirm the Product Quality before placing orders
A3  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q4  What's your MOQ
A4  Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5  How about delivery leadtime
A5  Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6  Is there a discount
A6  Different quantity has different discount.
Q7  How do you treat quality complaint
A7  First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q8  How to contact us
A9  You can chat with us by Trademanager,Skype, Wechat, Whatsapp Online.
       You can choose your interested products and send inquiry to us.
       You can dial our telephone directly or send Email to us., you will get our reply.