Hot Selling Manufacture Supply Raw Material Firocoxib Powder CAS 189954-96-9

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: BP USP EP IN-HOUSE
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Colour: White to off-White
• Quality: Refined
• CAS: 189954-96-9
• Storage: Normal Temperature
• Melting Point: 78-80°c
• Boiling Point: 563.9±50.0 °c
• Density: 1.31
• Einecs: 200-001-2
• Transport Package: Drum Bag
• Specification: 10kg/drum 1kg/bag
• Trademark: Jinan Andechem
• Origin: China
• Production Capacity: 100kg/Per Year

Product Description

Product Name	Firocoxib
CAS No.	189954-96-9
MF	C17H20O5S
Appearance	White to Off-White
Packing	10kg/drum 1kg/bag
Specification	BP, USP, EP
Shelf life	2 Years

Ferocoxib is an important non-steroidal anti-inflammatory veterinary drug. Its action is mainly to block the conversion of arachidonic acid to prostaglandins by selectively inhibiting cyclooxygenase-2 (COX-2) -mediated synthesis of prostaglandins, and then Chemicalbook produces antipyretic, analgesic and anti-inflammatory effects. Compared with other non-steroidal anti-inflammatory veterinary drugs, non-rocoxib can efficiently and selectively inhibit COX-2, and can be rapidly absorbed by the body, and has a significant effect on relieving pain in osteoarthritis.

Compound  A was used as the starting material to react with acetoxyacetyl chloride to form compound B. Compound B was added with DBU and reacted at 80ºC for at least 18h to obtain compound C. Compound C was then reacted with cyclopropyl bromide in the solvent DMF under the condition of NaH as base to form non-rocoxib.