Top Quality Hot Sale GMP Medemidine intermediates CAS: 86347-14-0 Security Clearance
Product Name |
Medemidine intermediates |
CAS No. |
86347-14-0 |
Packing |
1kg |
Appearance
|
white powder |
Total impurities |
0.44% |
Loss on drying
|
0.13% |
Residue on ignition
|
0.04% |
Assay
|
99.56% |
Dexmedetomidine, a highly selective α2 adrenergic receptor agonist, has sedative, hypnotic, analgesic, and anti-sympathetic effects and is widely used in clinical anesthesia and intensive care unit sedation. Dexmedetomidine is more and more used in the diagnosis and treatment of sleep disorders due to its characteristics of inducing Chemicalbook to induce similar physiological sleep, small respiratory depression, and strong neuroprotective effect. In addition, with the development of anesthesia therapy and sleep medicine in recent years, dexmedetomidine has been increasingly used in the diagnosis and treatment of sleep disorders.
Medetomidine(Domtor) is an α2 adrenergic receptor agonist with Ki of 1.08 nM and 1750 nM for α2 and α1 adrenergic receptors, respectively.Dexmedetomidine is a highly selective α2 adrenergic receptor agonist, which produces corresponding pharmacological effects by acting on α2 receptors in the central nervous system and peripheral nervous system. Dexmedetomidine can produce sedative and hypnotic effect by acting on the α2 receptor of locus coeruleus and activating the endogenous Chemicalbook sleep-promoting pathway, so that patients can maintain non-rapid eye movement stage III natural sleep state. This sedative and hypnotic state is characterized by patients can be awakened by stimulation or language, and there is no respiratory depression during sedation and hypnosis.
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A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
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A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6 Is there a discount
A6 Different quantity has different discount.
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