GMP Quality Veterinary Medicine Firocoxib CAS 189954-96-9 with Good Price

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Model NO.: BP USP EP IN-HOUSE
• Colour: White to off-White
• Quality: Refined
• CAS: 189954-96-9
• Storage: Sealed in Dry,Store in Freezer, Under -20°c
• Melting Point: 78-80°c
• Boiling Point: 563.9±50.0 °c
• Density: 1.31
• Einecs: 200-001-2
• Transport Package: Drum Bag
• Specification: 10kg/drum 1kg/bag
• Trademark: Jinan Andechem
• Origin: China
• Production Capacity: 100kg/Per Year

Product Description

    GMP High quality factory supply  Antibacterial Pradofloxacin CAS 195532-12-8

Product Name	Firocoxib
CAS No.	189954-96-9
MF	C17H20O5S
Appearance	White to Off-White
Packing	10kg/drum 1kg/bag
Specification	BP, USP, EP
Shelf life	2 Years

Tests	SPECIFICATIONS	RESULTS
Appearance	White to off white crystalline powder	White crystalline powder
Loss on Drying	≤0.5%	0.20%
Identification	UV:maximum absorption at 288nm,minimum absorption at 244nm.	Conform
	IR:corresponds to Firocoxib reference spectrum	Conform
	HPLC: Retention time of Firocoxib sample is consistent with that of reference standard in assay	Conform
Residual Solvents	Ethanol≤5000ppm	600ppm
	Heavy metals≤10ppm	<10ppm	<10ppm
	Residual on ignition≤10ppm	0.06%	0.06%
Related Substances	P0Z1not more than0.5%	Conform
	M1Z1not more than0.5%	Conform
	P0Z6not more than0.5%	Conform
	P0Z7not more than0.5%	0.10%
	M2Z4not more than0.5%	Conform
	Any other impurity not more than0.20%	0.08%
	Total impurities not more than2.0%	0.16%
	Purity≥99.0%	99.84%
Assay	98-102%	99.5%
Particle Size	90%<30um	Conform
Conclusion	The results conform to the Enterprise standard.

Ferocoxib is an important non-steroidal anti-inflammatory veterinary drug. Its action is mainly to block the conversion of arachidonic acid to prostaglandins by selectively inhibiting cyclooxygenase-2 (COX-2) -mediated synthesis of prostaglandins, and then Chemicalbook produces antipyretic, analgesic and anti-inflammatory effects. Compared with other non-steroidal anti-inflammatory veterinary drugs, non-rocoxib can efficiently and selectively inhibit COX-2, and can be rapidly absorbed by the body, and has a significant effect on relieving pain in osteoarthritis.

Compound  A was used as the starting material to react with acetoxyacetyl chloride to form compound B. Compound B was added with DBU and reacted at 80ºC for at least 18h to obtain compound C. Compound C was then reacted with cyclopropyl bromide in the solvent DMF under the condition of NaH as base to form non-rocoxib.